Activated matrix and method of activation

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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260112R, 2601125R, 260 6, 536 43, 536 44, 536 48, 536 49, 536 50, 536107, 536108, 536110, 536115, C08B 300

Patent

active

042244390

ABSTRACT:
Carbonylation of a polysaccharide and the product of that carbonylation. The carbonylated product can be used to prepare an affinity chromatography matrix which is an uncharged species of varying pH's. The carbonylated product is also useful for the preparation of other compounds. Typical polysaccharides are agarose, starch, dextran, cellulose and regenerated cellulose and typical carbonylating agents are N,N'-carbonyl diimidazole; N,N' carbonyl di-1,2,3-benzotriazole; and N,N'-carbonyl di-1,2,4-triazole.

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patent: 3793065 (1974-02-01), Morrison et al.
patent: 3833555 (1974-09-01), Keys et al.
patent: 3880832 (1975-04-01), Tessler
patent: 4020268 (1977-04-01), Nishikawa et al.

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