Activated immunodiagnostic pipette tips

Details Activated immunodiagnostic pipette tips Activated immunodiagnostic pipette tips

1991-05-06

1992-12-15

Warden, Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

422 57, 435288, 435291, B01L 302

Patent

active

051715376

ABSTRACT:
The tip has intermediate its end at least two axially spaced projections which are formed on the wall of its axial bore to extend radially and part way into the bore to define therebetween a reaction chamber in the bore of the tip. A spherical receptor element is mounted in the reaction chamber for limited pulsating movement therein in response to the movement of a fluid sample into and out of the tip. Additional projections may be formed in the bore to increase the turbulence created by the sample as it moves through the tip. The spherical element is coated with a ligand having a specific affinity for a target molecule in the sample.

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"Covalent Coupling Methods", Methods in Enzymology, vol. 44, pp. 138-145, 1976, Academic Press.
"New Supports in Solid Phase Sequencing", Methods in Enzymology, vol. 47, pp. 263-286, 1977, Academic Press.
"Target Amplification Systems in Nucleic Acid-based diagnostic Approaches", Kwoh et al., ABL, Oct. 1990.
"Polymerase Chain Reaction-Special Report", Arnheim et al., Chemical and Engineering News, Oct. 1, 1990.

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