Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell
Patent
1996-12-12
2000-01-25
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Animal or plant cell
424 937, 435 2, 435325, 435375, 435377, 435455, A01N 6300, C12N 510
Patent
active
060175273
ABSTRACT:
Antigen-expressing, activated dendritic cells are disclosed. Such dendritic cells are used to present tumor, viral or bacterial antigens to T cells, and can be useful in vaccination protocols. Other cytokines can be used in separate, sequential or simultaneous combination with the activated, antigen-pulsed dendritic cells. Also disclosed are methods for stimulating an immune response using the antigen-expressing, activated dendritic cells.
REFERENCES:
patent: 5525708 (1996-06-01), Nocka
patent: 5540926 (1996-07-01), Aruffo
patent: 5633234 (1997-05-01), August et al.
I. Morse et al. Cancer Research 58:2965-2968 (1998).
Grouard et al. J. Immunol. 155:3345-3352 (1995).
Calland et al. Immunol. Today 14:559-564 (1993).
Noelle et al. Immunol. Today 13:431-433 (1992).
Siena et al. Eptl. Hematol. 23:1463-1471 (1995).
Grouard et al. J. Immunol. 155:3345, 1995.
Van der Berg et al., Immunol. 88:294, 1996.
Peguet-Navarro et al., J. Immunol 155:4241, 1995.
Paglia et al., J. Exp. Med. 178:1893, 1993.
Levya-Cobian et al., Immunology Letters 43:29, 1994.
Girolomani et al., Eur. J. Dermatol. 5:12, 1995.
Jaiswal et al., Int'l. Immunol. 8:275, 1996.
Koch et al., J. Exp. Med. 184:741, 1996.
Caux et al., J. Exp. Med. 180:1263, 1994.
Sallusto et al., J. Exp. Med. 179:1109, 1994.
Ye et al., American Society of Hematology 37th Annual Meeting.
Gee et al., Keystone Mone Marrow Transplantation Symposia 1996.
Maraskovsky Eugene
Mc Kenna Hilary J.
Chan Christina Y.
Gambel Phillip
Henry Janis C.
Immunex Corporation
LandOfFree
Activated dendritic cells and methods for their activation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Activated dendritic cells and methods for their activation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activated dendritic cells and methods for their activation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2313829