Actaplanin antibiotics

Details Actaplanin antibiotics Actaplanin antibiotics

1983-04-27

1984-10-30

Brown, Johnnie R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

536 168, 536 181, C07C10352, C07H 1708

Patent

active

044798970

ABSTRACT:
Actaplanin antibiotics (A4696) designated as C.sub.2a, D.sub.1, D.sub.2, K, L, M, N, and O are obtained by the partial acidic hydrolysis of known actaplanins at about pH 1.85 for 2.5 hours at about 90.degree. C. The new actaplanins, like the known actaplanins, are glycopeptides which possess antibacterial activity and, either alone or as a mixture with other actaplanins, improve the feed efficiency in ruminants, swine and poultry.

REFERENCES:
patent: 3928571 (1975-12-01), Raun
patent: 3952095 (1976-04-01), Hamill et al.
patent: 4064233 (1977-12-01), Hamill et al.
patent: 4115552 (1978-09-01), Hamill et al.
patent: 4322343 (1982-03-01), Debono et al.
patent: 4322406 (1982-03-01), Debono et al.
Kalman, et al., J. Amer. Chem. Soc., 102, No. 3 (1980) 897-905.

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