Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1996-04-04
1999-01-12
Beisner, William H.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204450, 204451, 204600, 204601, G01N 2726, G01N 27447
Patent
active
058581880
ABSTRACT:
Microchannels having at least an acrylic inner surface and methods of their use in electrophoretic applications are provided. The subject microchannels may be in the form of a variety of configurations suitable for holding an electrophoretic medium. The subject microchannels give rise to substantially reduced EOF and/or adsorption as compared to fused silica under conditions of electrophoresis and find use in a variety of electrophoretic applications in which charged entities are moved through a medium under the influence of the an applied electric field.
REFERENCES:
patent: 4680201 (1987-07-01), Hjerten
patent: 4705616 (1987-11-01), Andresen et al.
patent: 4708782 (1987-11-01), Andresen et al.
patent: 5433989 (1995-07-01), Thakar et al.
Hjerten, "High-Performance Electrophoresis Elimination of Electroendosmosis and Solute adsorption," J. of Chromatography (1985), 347:191-198.
Cobb et al., "Electrophoretic Separations of Proteins in Capillaries with Hydrolytically Stable Surface Structures," Anal. Chem. (1990), 82:2478-2483.
Ratner, "Surface Modification of Polymers: Chemical, Biological and Surface Analytical Challenges," Biosensors & Bioelectronics (1995), 10:797-804.
Gilges et al., "Capillary Zone Electrophoresis Separations of Basic and Acidic Proteins Using Poly (vinyl alcohol) Coatings in Fused Silica Capillaries," Anal. Chem. (1994), 66:2038-2046.
Rohlicek et al., "Determination of the Isoelecrtic Point of the Capillary wWll in Capillary Electrophoresis Application to Plastic Capillaries," J. of Chromatography A (1994), 662:369-373.
Liu et al., "Polymeric Hollow Fibers for Capillary Electrophoresis," J. Microcol. (Sep. 1993), 245-253.
Nielen, "Capillary Zone Electrophoresis Using a Hollow Polypropylene Fiber," J. of High Resolution Chromatography (Jan. 1993), 16:62-24.
Schutzner and Kenndler, "Electrophoresis in Synthetic Organic Polymer Capillaries: Variation of Electroosmotic Velocity and .intg. Potential with pH and Solvent Composition," Anal. Chem. (1992), 64:1991-1995.
Soane David S.
Soane Zoya M.
ACLARA BioSciences, Inc.
Beisner William H.
Starsiak Jr. John S.
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