Acrylic copolymer membranes for biosensors

Details Acrylic copolymer membranes for biosensors Acrylic copolymer membranes for biosensors

1992-02-11

1994-02-08

Howell, Kyle L.

Surgery

Truss

Pad

204415, A61B 500

Patent

active

052841405

ABSTRACT:
Homogeneous membranes are disclosed which are composed of acrylic copolymers and are capable of absorbing 10% to 50% of their dry weight of water. The copolymers include a hydrophilic component which comprises acrylic esters having a poly(ethylene oxide) substituent as part of the alcohol moiety. The copolymers further comprise methacrylate and/or acrylate monomer units. The membranes are useful in the fabrication of biosensors, e.g., a glucose sensor, intended for in vivo use. Variations in the ratios of the monomeric components make possible the fabrication of membranes which have varying permeabilities.

REFERENCES:
patent: 3220960 (1965-11-01), Wichterle et al.
patent: 3912614 (1975-10-01), Spracklen et al.
patent: 4484987 (1984-11-01), Gough
patent: 4759828 (1988-07-01), Young et al.
patent: 4890620 (1990-01-01), Gough
patent: 5030333 (1991-07-01), Clark, Jr.
Chemical Abstracts, No. 17559u, vol. 101 (1984).
Chemical Abstracts, No. 17697r, vol. 106 (1987).
Chemical Abstracts, No. 223332p, vol. 107 (1987).
M. Kumakura and I. Kaetsu, "Physical Characterization and Molecular Structure of Hydrophilic Polymers Obtained by Radiation Cast-Polymerization of Methoxypolyethylene Glycol Methacrylate Monomers for Biomedical Applications," J. Mater Sci., 18(8), 2430-6 (1983).
S. Gernet, et al., "Fabrication and Characterization of a Planar Electrochemical Cell and its Application as a Glucose Sensor," Sensors and Actuators, 18, 59-70 (1989).
M. Shichiri, "Glycaemic Control in Pancreatectomized Dogs with a Wearable Artificial Endocrine Pancreas," Diabetologia, 24, 179-184 (1983).
M. E. Collison and M. E. Meyerhoff, "Chemical Sensors for Bedside Monitoring of Critically Ill Patients," Analytical Chemistry, 62, No. 7, 425-437 (1990).
P. Vadgama, "Biosensors: Adaptation for Practical Use," Sensors and Actuators, B1, Nos. 1-6, 1-7 (1990).
E. Wilkins and W. Radford, "Biomaterials for Implanted Closed Loop Insulin Delivery System," Biosensors & Bioelectronics, 5, No. 3, 167-213 (1990).
A. P. F. Turner and J. C. Pickup, "Diabetes Mellitus; Biosensors for Research and Management," Biosensors, 1, 85-115 (1985).
M. Shichiri, et al., "In Vivo Characteristics of Needle-Type Glucose Sensor-Measurements of Subcutaneous Glucose Concentrations in Human Volunteers"-Horm. Metab. Res., Suppl. Ser., 20:17-20 (1988).
J. Bruckel, et al., "In Vivo Measurement of Subcutaneous Glucose Concentrations with an Enzymatic Glucose Sensor and a Wick Method," Klin. Wochenschr., 67:491-495 (1989).
J. Pickup et al., "In Vivo Molecular Sensing in Diabetes Mellitus: An Implantable Glucose Sensor with Direct Electron Transfer," Diabetologia, 32:213-217 (1989).

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