Acrylacetamides

Details Acrylacetamides Acrylacetamides

1995-05-30

1996-07-02

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548453, 548568, C07D20736, C07D207325, A61K 3140

Patent

active

055322662

ABSTRACT:
Novel arylacetamides of the formula I ##STR1## in which Q is R.sup.4 --CH(CH.sub.2 Z)--NA--, ##STR2## R.sup.1 is Ar, cycloalkyl with 3-7 C atoms or C.sub.4 -C.sub.8 -cycloalkyl-C.sub.1 -C.sub.7 -alkyl,

REFERENCES:
patent: 4192883 (1980-03-01), Cousse
patent: 4806547 (1989-02-01), Giardina et al.
patent: 5091392 (1992-02-01), Raddatz et al.
Barber et al., "A pharmacological profile of the novel, peripherally-selective .kappa.-opioid . . . ", Br. J. Pharmacol (1994), 113, pp. 1317-1327.
Tarayre, et al., Arzneim-Forsch./Drug Res., 33(II), No. 7, pp. 931-935, 1983.
Hendrickson et al, Organic Chemistry, 3rd Edition, p. 513, 1970.
CA78(9) 58099r, Clemence et al, FR 2113786 patent abstract, Aug. 1972.
CA77(11) 75024; Clemence et al, DE 2155906 patent abstract, May 1972.

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