Acronycine derivatives

Details Acronycine derivatives Acronycine derivatives

1973-07-09

1976-03-09

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424257, C07D49104

Patent

active

039431371

ABSTRACT:
Acronycine derivatives having the structural formula: ##SPC1##
Wherein R is acyl and A is an anion of a suitably strong acid, stabilized formulations thereof and pharmaceutical compositions comprised of same exhibit broad spectrum antitumor activity, and are especially suited for intravenous administration.

REFERENCES:
patent: 3673163 (1972-06-01), Walkling
patent: 3843658 (1974-10-01), Smithwick, Jr.
T. R. Govindachari et al., Tetrahedron 22, 3245 (1966).

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