Acridinium compounds and conjugates thereof

Details Acridinium compounds and conjugates thereof Acridinium compounds and conjugates thereof

1995-04-28

1997-01-14

Weimar, Elizabeth C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530395, 530404, 530405, 530408, 530409, 536 221, 546102, 546104, 5483037, C07K 1600, C07D21908

Patent

active

055941125

ABSTRACT:
Acridinium compounds represented by the general formula (I) where A is an intervening group which does not have activity for binding with a specific binding substance, Z is a labelling active group which has activity for binding with a specific binding substance, R.sup.1 is a halogen atom, an alkyl group or an aryl group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each a hydrogen atom, an alkyl group, an aryl group, an alkoxy group, a nitro group, a halogen atom or a carbonyl group, and Y is a counter ion. The acridinium compounds may form conjugates with specific binding substances. The acridinium compounds have high emission efficiency and stability and, hence, are useful as chemiluminescence labelling agents.

REFERENCES:
patent: 4745181 (1988-05-01), Law et al.
patent: 4918192 (1990-04-01), Law et al.
patent: 4950613 (1990-08-01), Arnold, Jr. et al.
patent: 5110932 (1992-05-01), Law et al.
patent: 5151518 (1992-09-01), Dombrowski et al.
patent: 5227489 (1993-07-01), Law et al.
patent: 5241070 (1993-08-01), Law et al.
patent: 5281712 (1994-01-01), McCapra et al.
patent: 5283334 (1994-02-01), McCapra
patent: 5284951 (1994-02-01), McCapra et al.
patent: 5284952 (1994-02-01), Ramakrishnan
patent: 5321136 (1994-06-01), McCapra

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