Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-07-31
2000-07-11
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21900
Patent
active
06087502&
ABSTRACT:
Acridinium compounds and their conjugates exhibiting high chemiluminescence yield are provided. Such compounds may be used to enable a highly sensitive specific binding assay. The acridinium compounds are represented by formula (I): ##STR1## wherein A is a linker; Z is a binding group; Y is a counter ion; R.sup.1 and R.sup.2 are independently a substituent; p and m are independently an integer of from 0 to 4; n is an integer of from 2 to 5; and X is an organic intervening moiety with a functionality of at least n, having an aryloxy group or an arylsulfonamide group through which X binds to carbonyl carbon bonded to 9-position of the acridinium ring.
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Kifle Bruck
Mochida Pharmaceuticals Co., Ltd.
Shah Mukund J.
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