Acoustic tumor detection using stacked derived-band ABR amplitud

Details Acoustic tumor detection using stacked derived-band ABR amplitud Acoustic tumor detection using stacked derived-band ABR amplitud

1998-05-13

2000-06-27

Hindenburg, Max

Surgery

Diagnostic testing

Ear or testing by auditory stimulus

A61B 500

Patent

active

060801123

ABSTRACT:
A diagnostic procedure first records a patient's auditory brainstem response (ABR) to each of a plurality of auditory stimuli. The stimuli comprise 60 dB nHL clicks using high pass noise masking procedures to isolate the cochlear response within specific frequency bands. These derived band ABRs are temporally shifted to align the wave V peak amplitudes. The time-shifted responses are then summed to create the stacked ABR. The stacked wave V ABR amplitude is compared to a threshold value. The stacked wave V ABR amplitudes for patients having small (less than or equal to 1 cm.) intracanalicular tumors are measurably lower than those for otherwise similar individuals without tumors.

REFERENCES:
"Electrocochleography and Auditory Brainstem Electric Responses in Patients with Pontine Angle Tumors", Ann Otol Rhinol Laryngol 1980; 89 (suppl 75):1-19, J.J. Eggermont, M. Don, and D.E. Brackmann.
"Efficacy of Auditory Brainstem Response as a Screening Test for Small Acoustic Neuromas", Am J Otol 1995; 16:136-139 by M.L. Gordon and N.L. Cohen.
"The Auditory Brain Stem Response I-V Amplitude Ratio in Normal, Cochlear, and Retrocochlear Ears", Ear Hear 1984; 5:52-55, Musiek, Kibbe, Rackliffe, et al.
"Quality Estimation of Averaged Auditory Brainstem Responses", Elberling C., Don M., Scand Audiol 1984; 13:187-197.
"Evaluating Residual Background Noise in Human Auditory Brainstem Responses", Don M., Elberling C., J. Acoust Soc Amer 1994; 96:2746-2757.
"Estimation of Auditory Brainstem Responses, ABR, by Means of Bayesian Reference", Elberling C., Wahlgreen D., Scand Audiol 1985; 14:89-96.

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