Aconitane derivatives used as a medication to treat addiction

Details Aconitane derivatives used as a medication to treat addiction Aconitane derivatives used as a medication to treat addiction

1992-07-13

1994-03-01

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514810, 514812, A61K 3144

Patent

active

052907848

ABSTRACT:
This invention relates to a medication to treat addicts who are addicted to drugs or narcotics (including opium, morphine, heroine, cocaine, marijuana, amphetamine, etc.), the preparative method of this medication, as well as the treatment method for the addicts by using this medication. This medication to treat addiction is aconitane deivative having structures of formula I or II, wherein the formula I, R=.alpha.--OCH.sub.3, .beta.--OCH.sub.3 or .alpha.--OH; R.sub.1 =OAcABz, OH, OABz or H; R.sub.2 =H or OH; R.sub.3 =H or OH; R.sub.4 =H or OH; R.sub.5 =H or OH; R.sub.6 =OCH.sub.3, OBz, OAc or OH; wherein the formula II, R.sub.1 =R.sub.2 =R.sub.3 =OH.
This medication to treat addiction is characterized by no drug-dependence, high cure effect, fast action and low side effect. ##STR1##

REFERENCES:
patent: 4012505 (1977-03-01), Boici
patent: 4352796 (1982-10-01), Arichi et al.
patent: 4656178 (1987-04-01), Junusov et al.

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