Acne vulgaris treating

Details Acne vulgaris treating Acne vulgaris treating

1991-09-26

1993-04-06

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Hydrocarbon doai

514859, A61K 31015

Patent

active

052004295

ABSTRACT:
An acne vulgaris treating and preventing topica, which comprises, as an active ingredient, at least one compound selected from the group consisting of caryophyllene, cedrene, longifolene and thujopsene. The topica exhibits sufficient inhibitory activity on proliferation of Propionibacterium acnes, a pathogenic bacterium causing acne vulgaris, at a small therapeutic dose without causing skin irritation.

REFERENCES:
Chemical Abstracts 110:237000c (1989).
Chemical Abstracts 113:165123g (1990).
M. Yatagai et al., Biochemical Systematics and Ecology, 13(4), 377-385 (1985).
Osamu Okuda, Comprehensive Bibliography of Perfume Chemistry, vol. I, published by Hirokawa Publishing Co. on Jul. 5, 1967.
J. A. Morris et al., Journal of the American Oil Chemists' Society, 56, 595-603 (1979).
N. Diaz et al., An Real Acad. Farm., 54:526-531 (1988).
B. B. Dey et al., Indian Perfumer, 28(2), pp. 82-87, 1984.
Masaaki Ito et al., J. Antibact. Antifung. Agents, 8(1), pp. 3-6, 1980.

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