Acne preparation for oral administration

Details Acne preparation for oral administration Acne preparation for oral administration

1975-06-18

1977-11-08

Torrence, Dolph H.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

195 96, A61K 3902

Patent

active

040576272

ABSTRACT:
An acne preparation for oral administration and a method of preparing the same in which a nutrient medium, such as, meat-peptone broth is inoculated with Corynebacterium acnes, such as, Beck, Gerrath and Vogel strains and combinations thereof, fermentation is carried out, the Corynebacterium acnes are inactivated, preferably by treatment with ultrasonics, and freeze-dried, to form an immunizing constituent. This immunizing constituent is preferably mixed with metabolic products of Corynebacterium acnes as a desensitizing constituent, preferably antigens contained in the nutrient medium in which Corynebacterium acnes are cultivated. The composition may be made in the form of tablets, capsules or liquids, such as, emulsions or syrups, and may contain conventional adjuvants, carriers and/or auxiliary agents.

REFERENCES:
patent: 3651214 (1972-03-01), Raettig
Engman, J. Amer. Med. Ass., vol. 76, pp. 176-177 (1921).

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