Acne and psoriasis treatment with retinoic acid analogs

Details Acne and psoriasis treatment with retinoic acid analogs Acne and psoriasis treatment with retinoic acid analogs

1974-04-22

1976-01-20

Drezen, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424344, A61K 3120

Patent

active

039340287

ABSTRACT:
Skin diseases resulting from abnormal metabolic processes, such as acne and psoriasis, are treated on a repetitive basis, either internally or topically, with a dermatologically sufficient amount of 11-(2',6',6'-trimethylcyclohex-1'-enyl-1')-5,9-dimethylundeca-2,4,6,8,10-p entenoic acid or its physiologically acceptable salts to reduce the inflammation. The subject acid or its salts are found to provide remission of the dermatologically diseased condition, while avoiding side effects concommitant with the use of other analogous compounds.

REFERENCES:
patent: 3006939 (1961-10-01), Pommer et al.
patent: 3689667 (1972-09-01), Lee
patent: 3729568 (1973-04-01), Kligman
patent: 3882244 (1975-05-01), Lee
Stedman's Medical Dictionary, 21st Edition (1969) pp. 18 and 1432.
Chemical Abstracts (1961) 55: 7570(e).
Chemical Abstracts 56:512(d) (1962).
Chemical Abstracts 56: 8571(e) (1962).
Chemical Abstracts 56: 3915(d) (1962).
Current Therapy (1970) pp. 534-537.
Newman et al. American Perfumer and Aromatics 5/1959 pp. 44-46.
Redfearn, Arch. of Biochem. and Biophysics 91, 226-229 (1960).
Chemical Abstracts 56: 7372d (1962).

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