Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-25
1998-08-11
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549403, A61K 3135, C07D31130
Patent
active
057927898
ABSTRACT:
Acids and esters of diosmetin of formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are as defined in the description, and the physiologically tolerable salts thereof.
The said compounds can be used as medicaments in the treatment of chronic venous insufficiency and any other disorder involving hyperpermeability and/or inflammation.
REFERENCES:
patent: 2350804 (1944-06-01), Ohta
patent: 2897211 (1959-07-01), Da Re
patent: 3219531 (1965-11-01), Blaise
patent: 5629339 (1997-05-01), Wierzbicki et al.
Angiology 48, No. 7, 559-567 (1997).
Simpson, Sci. Proc. Royal Dublin Soc., vol. 27, pp. 111-117 1956.
Boussard Marie-Francoise
Vallez Marie-Odile
Verbeuren Tony
Wierzbicki Michel
Adir et Compagnie
Dentz Bernard
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