Acidic mammalian proteins and polynucleotides encoding the same

Details Acidic mammalian proteins and polynucleotides encoding the same Acidic mammalian proteins and polynucleotides encoding the same

2005-03-29

2005-03-29

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C514S012200, C514S021800, C530S300000, C530S324000

Reexamination Certificate

active

06872704

ABSTRACT:
Genes are disclosed that are differentially-regulated during feeding and fasting cycles. These genes, and their encoded polypeptides are useful to combat obesity and other metabolic disorders.

REFERENCES:
patent: 4469863 (1984-09-01), Ts'o et al.
patent: 5023243 (1991-06-01), Tullis
patent: 5130302 (1992-07-01), Spielvogel et al.
patent: 5177198 (1993-01-01), Spielvogel et al.
patent: 5223618 (1993-06-01), Cook et al.
patent: 5256775 (1993-10-01), Froehler
patent: 5264562 (1993-11-01), Matteucci
patent: 5264564 (1993-11-01), Matteucci
patent: 5366878 (1994-11-01), Pederson et al.
patent: 5378825 (1995-01-01), Cook et al.
patent: 5386023 (1995-01-01), Sanghvi et al.
patent: 5476925 (1995-12-01), Letsinger et al.
patent: 5489677 (1996-02-01), Sanghvi et al.
patent: 5508270 (1996-04-01), Baxter et al.
patent: 5539082 (1996-07-01), Nielsen et al.
patent: 5602240 (1997-02-01), De Mesmaeker et al.
patent: 5610289 (1997-03-01), Cook et al.
patent: 5623068 (1997-04-01), Reddy et al.
patent: 5700923 (1997-12-01), Goodchild et al.
patent: 5719262 (1998-02-01), Buchardt et al.
patent: WO 9417093 (1994-08-01), None
patent: WO 0123430 (2001-04-01), None
patent: WO 0136633 (2001-05-01), None
Boot et al. 2001, J. of Biol. Chem. vol. 276, No. 9, pp. 6770-6778.*
Aron, D., J. Fingling, and J. Tyrrell. 1997. Hypothalamus and pituitary. In Basic & clinical endocrinology/ F. Greenspan and G. Strewler, editors. Appleton & Lang, Stamford. 95-156.
Beck, B. 2001. KO's and organization of peptidergic feeding mechanisms.Neurosci Biobehav Rev. 25:143-58.
Bolivar, F., Rodriguez, R.L. Greene, P.J., Betlach, M.C., Heyneker, H.L. and Bayer, H.W. (1977) Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.Gene2:95-113.
Boot, R.G., E.F.C. Blommaart, E. Swart, K. Ghauharali-van der Vlugt, N. Bijl. C. Moe, A. Place, and J.M.F.G. Aerts. 2001. Identification of a Novel Acidic Mammalian Chitinase Distinct from Chitotriosidase.J. Biol. Chem. 276(9):6770-6778.
Boot, R.G., Renkema, G.H., Stryland, A., van Zonneveld, A.J. and Aerts, J.M. (1995). Cloning of cDNA encoding chitotriosidases, a human chitonase produced by macrophages.J. Biol. Chem. 270:26252-26256.
Cancela, J.M. 2001. Specific Ca2+ signaling evoked by cholecystokinin and acetylcholine: the roles of NAADP, cADPR, and IP3.Annu Rev Physiol. 63:99-117.
Clement, K., C. Vaisse, N. Lahlou, S. Cabrol, et al. 1998. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.Nature. 392:398-401.
Comuzzie, A.G., and D.B. Allison. 1998. The search for human obesity genes.Science. 280:1374-7.
Fusetti, F., H. von Moeller, Houston, D., Rozeboom, H.J., et al., Jul. 12, 2002. Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins.J. Biol. Chem., 277(28):25537-44.
Giraldo, P., Cenarro, A., Alfonso, P., Perez-Calvo, J.I., Rubio-Felix, D., Giralt, M. and Pocovi, M. (2001) Chitotriosidase genotype and plasma activity in patients type 1 Gaucher's disease and their relatives (carriers and non-carriers).Haematologica86:977-984.
Guan, X.M., H. Yu, and L.H. Van der Ploeg. 1998. Evidence of altered hypothalamic pro-opiomelanocortin
europeptide Y mRNA expression in tubby mice.Brain Res Mol Brain Res. 59:273-9.
Hill, J.O., and J.C. Peters. 1998. Environmental contributions to the obesity epidemic.Science. 280:1371-4.
Hollack, C.E., van Weely, S., van Oeis, M.H. and Aerts. J.M. (1994) Marked evelation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease.J. Clin. Invest. 93:1288-1292.
Kersten, S. 2001. Mechanisms of nutritional and hormonal regulation of lipogenesis.EMBO Rep. 2:282-6.
Montague, C.T., I.S. Farooqi, J.P. Whitehead, M.A. Soos, et al. 1997. Congenital leptin deficiency is associated with severe early-onset obesity in humans.Nature. 387:903-8.
Nakazato, M., N. Murakami, Y.Date, M. Kojima, et al. 2001. A role for ghrelin in the central regulation of feeding.Nature. 409:194-8.
Norman, R.A., C. Boigardus, and E. Ravussin. 1995. Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians.J Clin Invest. 96:158-62.
Owhashi, M., H. Arita, and N. Hayai. 2000. Identification of a Novel Eosinophil Chemotactic Cytokine (ECF-L) as a Chitinase Family Protein.J. Biol. Chem. 275(2):1279-1286.
Peptide Nucleic Acids (PNA): Synthesis, Properties and Potential Applications.Bioorganic and Medicinal Chemistry4:5-23 (1996).
Phillips, M.S., Q. Liu, H.A. Hammond, V. Dugan, et al. 1996. Leptin receptor missense mutation in the fatty Zucker rat.Nat Genet. 13:18-9.
Renkema, G.H., Boot, R.G., Muysers, P.O., Donker-Koopman, W.E. and Aerts, J.M. (1995). Purification and characterizations of human chitotriosidase, a novel member of the chitanase family of proteins.J. Biol. Chem. 270:2198-2202.
Ruppert, S., Wang, E.H. and Tjian, R. (1993) Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulats.Nature. 362:175-179.
Sakurai, T., A. Amemiya, M. Ishii, I. Matsuzaki, et al. 1998. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.Cell. 92:573-85.
Sakurai, T., A. Amemiya, M. Ishii, I. Matsuzaki, et al. 1998. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G. protein-coupled receptors that regulate feeding behavior.Cell. 92:1 page following 696.
Schrauwen, P., K. Walder, and E. Ravussin. 1999. Human uncoupling proteins and obesity.Obes Res. 7:97-105.
Shimkets, R.A., D.G. Lowe, J.T. Tai, P. Sehl, et al. 1999. Gene expression analysis by transcript profiling coupled to a gene database query.Nat Biotechnol. 17:798-803.
Sompayrac, L.M. & Darma, K.J. (1981) Efficient infections of monkey cells with DNA of simian virus 40.Proc. Natl Acad Sci USA78:7575-7578.
Spiegelman, B.M., and J.S. Flier. 1996. Adipogenesis and obesity: rounding out the big picture.Cell. 87:377-89.
Strosberg, A. D. 1997. Structure and function of the beta 3-adrenergic receptor.Annu Rev Pharmacol Toxicol. 37:421-50.
Suziki, M., W. Fugimoto, Goto, M., et al., Aug. 2002 Cellular expression of gut chitinase mRNA in the gastrointestinal tract of mice and chickens.J. Histochem. Cytochem, 50(8):1081-9.
Weigle, D.S., and J.L. Kuijper. 1996. Obesity genes and the regulation of body fat content.Bioessays. 18:867-74.
Wikberg, J.E., R. Muceniece, I. Mandrika, P. Prusis, et al. 2000. New aspects on the melanocortins and their receptors.Pharmacol Res. 42:393-420.
Yaswen, L., N. Diehl, M.B. Brennan, and U. Hochgeschwender. 1999. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin.Nat Med. 5:1066-70.
Young, E., C. Chatterton, Vellodi, A., and Winchester, B., Aug. 1997. Plasma chitotriosidase activity in Gaucher disease patients who have been treated either by bone marrow transplantation or by enzyme replacement therapy with alglucerase.J. Inherit. Metab. Dis., 20(4):595-602.
Boot, R.G., et al. Accession No. AAG60018.
Boot, R.G., et al., Accession No. AAG60019.
Boot, R.G., et al., Accession No. AF290003.
Boot, R.B., et al., Accession No. AF290004.
Saito, A., et al. Accession No. NM_021797.
Strasberg, R. Accession No. BC011134.

Affiliated with

Also associated with

Rating

Acidic mammalian proteins and polynucleotides encoding the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Acidic mammalian proteins and polynucleotides encoding the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acidic mammalian proteins and polynucleotides encoding the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3414833