Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines

Details Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines

1982-08-11

1986-10-28

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

514252, 544230, 544295, 544296, C07D29512

Patent

active

046200061

ABSTRACT:
Novel 1-(cyanoalkyl)-4-guanylpiperazine acid salts are prepared by reacting novel 1-(cyanoalkyl)piperazines with cyanamide in the presence of an acid. The novel 1-(cyanoalkyl)-4-guanylpiperazine acid salts are advantageously employed to prepare 1-(cyanoalkyl)-4-(2-pyrimidyl)piperazines by reacting them with malonaldehyde in an acidic medium.

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