Acid polycyclic ether antibiotic

Details Acid polycyclic ether antibiotic Acid polycyclic ether antibiotic

1991-01-28

1991-11-12

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549343, A61K 3135, C07D31100

Patent

active

050648551

ABSTRACT:
An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Streptomyces sp. ATCC 53862. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.

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Occolowitz et al. in Westley, ed., "Polyether Antibiotics, Naturally Occurring Acid Ionophores," vol. 2, Marcel Dekker, Inc., New York and Basel, 1982, pp. 197, 219-223.
Merck Index, Tenth Edition, Merck & Co., Inc., Rahway, N.J., 1983, monograph 6100 at p. 893.

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