Acid-labile subunit (ALS) of insulin-like growth factor binding

Details Acid-labile subunit (ALS) of insulin-like growth factor binding Acid-labile subunit (ALS) of insulin-like growth factor binding

1992-12-11

1994-06-28

Hill, Jr., Robert J.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530412, 530413, 435 691, C07K 1300

Patent

active

053248201

ABSTRACT:
An acid-labile protein is described that, when incubated with the 53-Kd acid-stable protein occupied by IGF, converts it to a high molecular weight complex, corresponding to the in vivo form of IGF. This protein is called the acid-labile subunit (ALS) of IGF binding protein complex and is provided in biologically pure form. ALS is useful in treating wounds and promoting cellular growth.

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