Acid anhydrides as rate controlling agent for the erosion of pol

Details Acid anhydrides as rate controlling agent for the erosion of pol Acid anhydrides as rate controlling agent for the erosion of pol

1982-06-30

1984-12-18

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, 424 78, A61K 922, A61K 926, A61K 952, A61K 3174

Patent

active

044890567

ABSTRACT:
The invention relates to the use of an acid anhydride incorporated as a latentiated catalyst in poly(ortho ester) and other polymers such that upon exposure to aqueous environments the acid anhydride generates the corresponding acid which catalyzes the matrix erosion. The releasing rate of a loaded drug substance incorporated into or surrounded by the poly(ortho ester) or other polymers can be controlled in that the drug is released as the poly(ortho ester)s or other polymer is eroded by action of the acid anhydride incorporated therein.

REFERENCES:
patent: 4093709 (1978-06-01), Choi et al.
patent: 4304767 (1981-12-01), Heller et al.

Affiliated with

Also associated with

Rating

Acid anhydrides as rate controlling agent for the erosion of pol does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Acid anhydrides as rate controlling agent for the erosion of pol, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acid anhydrides as rate controlling agent for the erosion of pol will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1988166