Acetylsalicylic acid thioesters, a process for their preparation

Details Acetylsalicylic acid thioesters, a process for their preparation Acetylsalicylic acid thioesters, a process for their preparation

1983-08-09

1986-01-07

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

260455R, 514513, 536 74, A61K 31265, A61K 3171, C07C153023, C07J 1500

Patent

active

045634432

ABSTRACT:
Acetylsalicylic acid thioesters having antipyretic activity and useful for the symptomatic treatment of influenza of formula: ##STR1## wherein n is zero or 1, R.sub.1 is hydrogen, methyl or carboxy and R.sub.2 is hydrogen or an acetamido group; a process for their preparation by reacting a functional derivative of acetylsalicylic acid with the suitable thiol; and pharmaceutical compositions containing them as active ingredient.

REFERENCES:
patent: 4256761 (1981-03-01), Suh et al.
Noller, Textbook of Organic Chemistry, 3rd Ed., W. B. Saunders Co., Philadelphia, 1966, p. 261.

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