Acetylenyl-pyrazolo-pyrimidine derivatives

Details Acetylenyl-pyrazolo-pyrimidine derivatives Acetylenyl-pyrazolo-pyrimidine derivatives

2007-07-03

2007-07-03

Rao, Deepak (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S259100

Reexamination Certificate

active

11375834

ABSTRACT:
The present invention relates to compounds of formula (I):wherein R1to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.

REFERENCES:
patent: 3725428 (1973-04-01), Janiak
patent: 4028374 (1977-06-01), Pelosi, Jr. et al.
patent: 4178449 (1979-12-01), Dusza et al.
patent: 4408047 (1983-10-01), Baldwin et al.
patent: 5099021 (1992-03-01), Worther et al.
patent: 6638933 (2003-10-01), Gerlach et al.
patent: 6730789 (2004-05-01), Birault et al.
patent: 6878720 (2005-04-01), Altmann et al.
patent: 6958341 (2005-10-01), Wilde et al.
patent: 2003/0139426 (2003-07-01), Wilde et al.
patent: 1 953 149 (1970-05-01), None
patent: 0 199 400 (1986-10-01), None
patent: 295 656 (1988-12-01), None
patent: 0343893 (1989-11-01), None
patent: 0404440 (1990-12-01), None
patent: 427 963 (1991-05-01), None
patent: 0604657 (1994-07-01), None
patent: 0 891 978 (1999-01-01), None
patent: 0 891 978 (1999-01-01), None
patent: 2 753 970 (1998-04-01), None
patent: 1 345 552 (1974-01-01), None
patent: 1 538 822 (1979-01-01), None
patent: WO 99/37630 (1990-01-01), None
patent: WO 97/29109 (1997-08-01), None
patent: WO 99/24035 (1999-05-01), None
patent: WO 00/18767 (2000-04-01), None
patent: WO 00/27819 (2000-05-01), None
patent: WO 01/19360 (2000-09-01), None
patent: WO 01/097786 (2001-12-01), None
patent: WO 02/083652 (2002-10-01), None
patent: WO 02/092086 (2002-11-01), None
patent: WO 03/048132 (2003-06-01), None
patent: WO 03/049741 (2003-06-01), None
patent: WO 03/053946 (2003-07-01), None
patent: WO 04/092135 (2004-10-01), None
patent: WO 04/111040 (2004-12-01), None
patent: WO 05/040171 (2005-05-01), None
patent: WO 05/123738 (2005-12-01), None
D'Onofrio, et al., J. Neurochem. (Mar. 2003) vol. 84(6) pp. 1288-1295.
Database Chemcats Online, Chemical Abstract Service, Columbus, Ohio, US, XP002316354.
Fraley et al., Bioorg. Med. Chem. Lett., 12, pp. 3537-3541 (2002).
Poulsen, et al., Bioorganic & Medicinal Chemistry, vol. 6 (1998) pp. 619-641.
Müller, et al., Bioorganic & Medicinal Chemistry, vol. 6, (1998) pp. 707-719.
Kim, et al., J. Med. Chem., (1998), vol. 41, pp. 2835-2845.
Li, et al., J. Med. Chem., (1998), vol. 41, pp. 3186-3201.
Baraldi, et al., J. Med. Chem., (1998), vol. 41, pp. 2126-2133.
Li, et al., J. Med. Chem., (1999), vol. 42, pp. 706-721.
Baraldi, et al., J. Med. Chem., (1996), vol. 39, pp. 1164-1171.
Colotta, et al., Arch. Pharm. Pharm. Med. Chem., vol. 332, pp. 39-41 (1999).
Auchampach, et al., Am. J. Physiol. vol. 276, H1113-1116 (1999).
Haas, et al., Naunyn-Schmiedeberg's, Arch. Pharmacol. vol. 362, pp. 375-381 (2000).
Patent Abstracts of Japan, vol. 1999, No. 10, JP 11 130761a.
Pandeya, S. N. et al., Indian Drugs (1985), 23(3), 146-51.
Daidone, G. et al., II Farmaco vol. 44, No. 5 (1989), pp. 465-473.
The Merck Index 12th Ed. (1996) p. 506.
Abstract corresponding to FR 2 753 970 (B14).

Affiliated with

Also associated with

Rating

Acetylenyl-pyrazolo-pyrimidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Acetylenyl-pyrazolo-pyrimidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acetylenyl-pyrazolo-pyrimidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3806324