Acetylenic imidazoles having central nervous system activity

Details Acetylenic imidazoles having central nervous system activity Acetylenic imidazoles having central nervous system activity

1991-01-22

1992-03-31

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514326, 514399, 546210, 548336, 548337, 548341, A61K 31415, A61K 31445, C07D40312, C07D40112

Patent

active

051009099

ABSTRACT:
Acetylenic imidazole compounds having cholinergic agonist or antagonist activity useful in the treatment of mental disorders, extrapyramidal motor disorders, disorders of the parasympathetic nervous system and glaucoma or as analgesics for the treatment of pain. Typical central nervous system disorders for which the subject compounds can be used include cognitive disorders of all ages, including senile dementia, Alzheimer's disease and other related disorders. The compounds are particularly developed to improve mental performance when a mental deficiency is diagnosed.

REFERENCES:
patent: 3925411 (1975-12-01), Dahlbom
patent: 3959311 (1976-05-01), Dahlbom
patent: 4463001 (1984-07-01), Melloni et al.
patent: 4721783 (1988-01-01), Davis
Press et al., J. Med. Chem., 29, 816-819 (1986).
Ringdahl, B., J. Med. Chem. 31, No. 3, 683-688 (1988).
Nilsson, et al, J. Med. Chem., 31 No. 3, 577-582 (1988).

Affiliated with

Also associated with

Rating

Acetylenic imidazoles having central nervous system activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Acetylenic imidazoles having central nervous system activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acetylenic imidazoles having central nervous system activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2259571