Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents

Details Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents

1998-08-25

1999-07-20

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514406, 544140, 544363, 544371, 546175, 546211, 5462754, 5483657, A61K 31415, A61K 3147, C07D23112, C07D40112

Patent

active

059257695

ABSTRACT:
Compounds of Formula I ##STR1## wherein, R.sub.1 through R.sub.7 are described herein. These compounds inhibit the production of arachidonic acid products associated with 5-lipoxygenase and cyclooxygenase and are useful in the treatment of inflammatory disorders.

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patent: 5516789 (1996-05-01), Brooks et al.
patent: 5559144 (1996-09-01), Brooks et al.
patent: 5616596 (1997-04-01), Basha et al.
patent: 5681966 (1997-10-01), Cai et al.
Scifinder Alkynyll Hydroxyurea Search Results Aug. 20, 1998.

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