Acetylene derivatives as inhibitors of histone deacetylase

Details Acetylene derivatives as inhibitors of histone deacetylase Acetylene derivatives as inhibitors of histone deacetylase

2008-05-06

2008-05-06

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S156000, C546S304000, C546S143000, C548S321500, C548S326500, C548S557000, C549S424000

Reexamination Certificate

active

10922119

ABSTRACT:
The present invention is directed to certain hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.

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