Acetylene amines and their use as vasodilators and antihypertens

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514338, 514347, 514349, 514351, 514412, 514414, 514422, 514424, 514426, 514427, 514443, 514444, 514445, 514447, 514438, 514452, 514465, 514466, 514471, 549495, 549492, 549491, 549480, 549479, 549473, 549443, 549441, 549440, 549435, 549362, 549 77, 549 75, 549 74, 549 68, 549 62, 549 60, 549 50, 548561, 548526, 548453, 546337, 546335, 546334, 546329, 546312, 546311, 546304, 546270, 546115, 564382, 564381, 564374, 564361, 564355, 564288, 564287, 564165, 564164, 564162, 560142, 560138, A61K 3144, A61K 3138, A6

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047256028

ABSTRACT:
Acetylenes of the following formula (I): ##STR1## wherein Y, m, R.sup.1, R.sup.2, R.sup.3, n and R.sup.4 are defined herein and R.sup.5 is hydrogen, alkyl, cycloalkyl or substituted alkyl are useful vasodilators and antihypertensives.

REFERENCES:
patent: 3719712 (1973-03-01), Remy
patent: 4128656 (1978-12-01), Lafon
patent: 4412856 (1983-11-01), Brunner et al.

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