Acetic acid ester of haloperidol

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546218, A61K 31435, C07D21152

Patent

active

048553077

ABSTRACT:
The present invention relates to the novel acetic acid ester of 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butano ne, as well as pharmaceutically acceptable acid addition salts thereof, a method of preparation, pharmaceutical compositions and a method of treating psychoses by administering said ester to an animal or human body.

REFERENCES:
patent: 3408356 (1968-10-01), Horovitz
patent: 4070473 (1978-01-01), Hernestom et al.
Chemical Abstracts: 97 60926U; E. Suy et al., "Bioavailability and Clinical Effects of Two Different Concentrations of Haloperidol decanoate", (1982).
Chemical Abstracts 94: 180676X, C. Niemegeers, "Parental Psychotropic Preparation with Long Term Action", (1981).

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