Acetic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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514212, 514307, 514317, 514327, 514331, 514352, 514538, 514564, 540593, 540594, 540606, 546192, 546216, 546221, 546304, 546323, 562440, C07C22928, C07C22902

Patent

active

059731885

ABSTRACT:
Acetic acid derivatives of the formula ##STR1## wherein L, M, T and Q have the significance given in the description, can be used for the treatment or prophylaxis of illnesses which are caused by the binding of adhesive proteins to blood platelets and by blood platelet aggregation and cell--cell adhesion, and are manufactured by cleaving protecting groups in the corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitrites.

REFERENCES:
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patent: 5084466 (1992-01-01), Alig et al.
patent: 5256812 (1993-10-01), Alig et al.
patent: 5273982 (1993-12-01), Alig et al.
patent: 5378712 (1995-01-01), Alig et al.
patent: 5399585 (1995-03-01), Alig et al.
patent: 5576444 (1996-11-01), Himmelsbach
Alig, et al., J. Med. Chem. 35:4393-4407 (1992) "Low Molecular Weight, Non-Peptide Fibrinogen Receptor Antagonists".
Alexander J et al. J. Med. Chem. 31(2), 318-322, 1988.

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