Acetic acid derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514318, 514326, 514327, 514330, 514331, 546 21, 546 22, 546 24, 546 25, 546192, 546193, 546194, 546208, 546220, 546222, 546224, A61K 31445, A61K 3143, C07D21192, C07D21108

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active

057261857

ABSTRACT:
Acetic acid derivatives of the formula ##STR1## wherein L, M, T and Q have the significance given in the description, can be used for the treatment or prophylaxis of illnesses which are caused by the binding of adhesive proteins to blood platelets and by blood platelet aggregation and cell-cell adhesion, and are manufactured by cleaving protecting groups in the corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitriles.

REFERENCES:
patent: 5039805 (1991-08-01), Alig et al.
patent: 5084466 (1992-01-01), Alig et al.
patent: 5256812 (1993-10-01), Alig et al.
patent: 5273982 (1993-12-01), Alig et al.
patent: 5378712 (1995-01-01), Alig et al.
patent: 5399585 (1995-03-01), Alig et al.
Alig, et al., J. Med. Chem. 35:4393-4407 (1992) "Low Molecular Weight, Non-Peptide Fibrinogen Receptor Antagonists".

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