Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Compounds related to acetazolamide and to its N-methyl derivatives, of the formulae: ##STR1## wherein Y is one of the following groups: ##STR2## R.sub.1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
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Article by P. G. DeBenedetti et al., "A Quantum Chemical QSAR Analysis of Carbonic Anhydrase Inhibito by Heterocyclic Sulfonamides, Sulfonamide Carbonic Anhydrase Inhibitors: Quantum Chemical QSAR".
Lo Baido Giuseppe
Carr Deborah D.
Dees Jos,e G.
Instituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
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