Acetaminophen compositions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Reexamination Certificate

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Details

C424S454000, C424S456000

Reexamination Certificate

active

07029698

ABSTRACT:
The invention herein provides for an oral pharmaceutical composition adapted for use in capsular dosage forms comprising acetaminophen and a lactate salt alone or in combination with an acetate salt. Compositions of the invention exhibit improved solubility characteristics of the active ingredient per given fill volume, thereby permitting the use of smaller capsule sizes to deliver a given effective dose of the active ingredient. Compositions of the invention also exhibit improved clarity per concentration of active ingredient. The invention also provides for a capsular dosage form containing the composition.

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patent: 4786725 (1988-11-01), Amundsen et al.
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patent: 5505961 (1996-04-01), Shelley et al.
patent: 5529923 (1996-06-01), Honour et al.
patent: 5735105 (1998-04-01), Stroud et al.
patent: 6020007 (2000-02-01), Veech
patent: 6160020 (2000-12-01), Ohannesian et al.

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