Acetamidoxime derivatives and use thereof

Details Acetamidoxime derivatives and use thereof Acetamidoxime derivatives and use thereof

1976-12-09

1978-11-07

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, 424267, 424274, 424285, 2603265D, 26034673, 544153, 544376, 546196, C07D29512, A61K 31535

Patent

active

041247108

ABSTRACT:
The invention relates to acetamidoxime derivatives represented by the general formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 represents a branched- or straight-chain alkyl group containing from 1 to 4 carbon atoms or a phenyl group, A represents one of the groups: ##STR2## R.sub.2 represents an amino group such as, for example, a dimethylamino, diethylamino, di-n-propylamino, di-n-butylamino, pyrrolidino, morpholino, piperidino or heptamethyleneimino group or a 1-piperazino group substituted in the 4-position by a straight-chain alkyl group containing from 1 to 4 carbon atoms, X represents a hydrogen or chlorine atom or a methoxy group and n is the integer 2 or 3.
The compounds of formula I have been found to be potentially useful in the treatment of disorders of arterial pressure.

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