Acetamidoxime compounds

Details Acetamidoxime compounds Acetamidoxime compounds

1976-03-18

1977-08-09

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260559A, 260562N, 424324, C07C10328, C07C10376, C07C103365, A61K 31165

Patent

active

040410722

ABSTRACT:
Compounds having the formula ##STR1## wherein R is hydrogen, or chlorine, or alkyl having one to 4 carbons, or alkoxy having one to 3 carbons, and R.sub.1 is hydrogen, or ##STR2## or --CONH--R.sub.3, wherein R.sub.2 is hydrogen, or chlorine, or nitro, or alkoxy having no more than 3 carbons, or trifluoromethyl, and R.sub.3 is alkyl having one to 4 carbons, or cycloalkyl having no more than 6 carbons, or phenyl.
The compounds are prepared by reacting R-substituted cyano-2 acetanilides with hydroxylamine to obtain compounds in which R.sub.1 is hydrogen, and then reacting with acid chlorides containing R.sub.2 or isocyanates containing R.sub.3. The compounds possess psychtropic properties.

REFERENCES:
patent: B533652 (1976-03-01), Cherkofsky
patent: 3414614 (1968-12-01), Julia
patent: 3560555 (1971-02-01), Fucho
patent: 3624151 (1971-11-01), Gutman
patent: 3636111 (1972-01-01), Karten
patent: 3766270 (1973-10-01), Hiller et al.
patent: 3819700 (1974-06-01), Bellina
patent: 3867447 (1975-02-01), Cherkofsky
patent: 3872169 (1975-03-01), Bellina

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