Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1993-09-15
1995-07-04
Kumar, Shailendra
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514456, 514520, 514619, 514622, 514866, 549398, 549404, 549407, 558404, 558413, 564166, 564167, 564172, 564174, 564175, 564180, 564181, 564183, A61K 31165, C07C23357
Patent
active
054300606
ABSTRACT:
The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.
REFERENCES:
patent: 3882247 (1975-05-01), Bullock
patent: 4053633 (1977-10-01), Goralski
patent: 4309554 (1982-01-01), Goralski
patent: 4567004 (1986-01-01), Blank et al.
patent: 4670470 (1987-06-01), Firestone
patent: 4831045 (1989-05-01), Tanouchi
patent: 5153227 (1992-10-01), Brown et al.
patent: 5270342 (1993-12-01), Brittain et al.
Brown et al, Chemical Abstracts 112: 7166y Jan. 1, 1990.
STN Printout, 9th Collective Index, Aug. 1978.
J. Chem. Soc., Chemical Communications, 1984, 670.
J. Organic Chemistry, 1978, 43, 3101.
J. Chem. Soc., Chemical Communications, 1978, 362.
J. Organic Chemistry, 1986, 51, 1012-1015.
Chemical Abstracts, vol. 104, Abstract No. 168055, 1986.
J. Prakt. Chem., 1920, 101, 136-137 (Chemical Abstracts vol. 15, 1013-1014).
Rec. Trav. Chim. Pays Bas, 1974, 93, 11-14.
J. Polymer Science, Polymer Chemistry Edition, 1985, 23, 1963-1972.
J. Heterocyclic Chemistry, 1977, 1415-1416.
Tetrahedron, 1969, 25, 181-189.
Chemical Abstracts, 104, Abstract No. 19503d, 1986.
Chemical Abstracts, 103, No. 12, 23 (1985).
Chemical Abstracts 88, No. 19 (1978).
Brown et al., Chemical Abstracts 112, 7166y, Jan. 1, 1990.
Brittain David R.
Brown Steven P.
Cooper Anthony L.
Longridge Jethro L.
Morris Jeffrey J.
Kumar Shailendra
Zeneca Limited
LandOfFree
Acetamide derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Acetamide derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acetamide derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-760535