Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-05-04
1999-03-02
Hutzell, Paula K.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530413, 530414, 530415, 530417, 530418, 530419, 530421, 530422, A23J 100, C07K 100
Patent
active
058772987
ABSTRACT:
A fimbrial agglutinogen preparation is prepared from a bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. The fimbrial agglutinogen preparation may be used to prepare acellular pertussis vaccines with other pertussis antigens, including pertussis toxin or toxoid thereof, the 69 kDa protein and filamentous hemagglutinin and other Bordetella antigens.
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Barreto Luis
Fahim Raafat E. F.
Herbert Andrew
Jackson Gail E. D.
Klein Michel H.
Duffy Patricia A.
Hutzell Paula K.
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