Acellular immunogenic compositions and acellular vaccine...

Details Acellular immunogenic compositions and acellular vaccine... Acellular immunogenic compositions and acellular vaccine...

2005-12-27

2005-12-27

Graser, Jennifer E. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S234100, C424S236100, C424S235100, C424S193100, C424S197110, C424S200100, C530S350000, C435S242000, C435S252300, C435S252310

Reexamination Certificate

active

06979449

ABSTRACT:
The invention concerns an acellular immunogenic or vaccine composition for producing antibodies againstBacillus anthraciscomprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains ofBacillus anthracisand their uses.

REFERENCES:
patent: 0 739 981 (1996-10-01), None
Kraevets et al. Microbiol. Res. Instit. Jul. 1998. Derwent abstract only.
Pezard et al. Infect. Immun. 1995. 63(4): 1369-1372.
Ivins et al. Infect. Immun. May 1986. 52(2): 454-7.
Ivins et al. Eur. J. Epidem. Mar. 1988. 4(1): 12-19.
S.L. Welkos et al.: “Comparative safety and efficacy againstBacillus anthracisof protective antigen and live vaccines in mice” Microbial Pathogenesis, vol. 5, No. 3, pp. 127-140 1988.
P.C.B. Turnbull: “ Anthrax vaccines: past, present, and future” Vaccine, vol. 9, No. 8, pp. 533-539 Aug. 1, 1991.
A.V. Stepanov et al.: “Development of novel vaccines against anthrax in man” Journal of Biotechnology, vol. 44, No. 1, pp. 155-160 Jan. 26, 1996.
V.A. Abalakin et al.: “Protective and other biological properties ofBacillus anthracissoluble antigen” Journal of Hygiene, Epidemiology, Microbiology, and Immunology, vol. 35, No. 1, pp. 83-91 1991.

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