Acellular antibordetella vaccine

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales

Reexamination Certificate

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C424S093300, C424S093200, C424S253100, C424S254100, C424S282100, C424S234100, C435S071100, C435S071200, C435S071300, C435S261000, C435S308100

Reexamination Certificate

active

07465443

ABSTRACT:
The invention relates to an immunogenic composition, characterized in that it comprises an adenyl cyclase-hemolysin (AC-Hly) protein, or an immunogenic portion of this AC-Hly, of a strain ofBordetellachosen fromB. pertussis, B. parapertussisorB. bronchiseptica,and in that it comprises, in addition, a bacterial extract containing the expression products of the vrg genes of a strain ofBordetellachosen fromB. pertussis, B. parapertussisorB. bronchiseptica,or a portion of these expression products which is sufficient to induce an immune response in a host to which the extract might be administered.

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