Access valve devices, their use in separation apparatus and corr

Details Access valve devices, their use in separation apparatus and corr Access valve devices, their use in separation apparatus and corr

1997-03-26

1999-05-11

Therkorn, Ernest G.

Liquid purification or separation

Processes

Chromatography

210659, 2101982, 210281, B01D15/08

Patent

active

059024852

ABSTRACT:
An access valve suitable for controlling fluid flow into and out of a chromatography column has relatively movable valve elements preferably represented by a central axially movable probe with a head acting as a spool valve in a barrel. Axial movement of the probe adjusts the valve between a fully open condition, in which both a first conduit extending through the probe and a second conduit defined around the probe are open to the column interior, and a partly open condition in which a sealing component of the probe closes the second conduit. Also, further axial movement of the probe provides a fully closed position in which both conduits are closed. The partly open position is useful for packing chromatography media into its column while the third position is useful for unpacking the same. In the closed condition of the valve, the first and second conduits communicate with one another so that the valve interior can be cleaned while the column is operating.

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