Liquid purification or separation – With means to add treating material – Chromatography
Patent
1998-09-21
2000-07-18
Therkorn, Ernest G.
Liquid purification or separation
With means to add treating material
Chromatography
210281, 210656, 210659, B01D 1508
Patent
active
060902795
ABSTRACT:
An access valve suitable for controlling fluid flow into and out of a chromatography column has a central axially movable probe with a head (71) acting as a spool valve in a barrel (6). Axial movement of the probe adjusts the valve between a fully open condition, in which both a first conduit (73) extending through the probe and a second conduit (51) defined around the probe are open to the column interior, a partly open condition in which a second sealing land (76) on the probe closes the second conduit (51), and a fully closed position in which both conduits are closed. The three positions are useful for packing and unpacking chromatography media into and from the column. In the closed condition of the valve, the first and second conduits (73, 51) communicate with one another so that the valve interior can be cleaned while the column is operating.
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Inventor sketch of device operating in Italy and supplied by Amicon (UK) (Undated).
Davis John
Hofmann Martin John
Amersham Pharmacia Biotech AB
Therkorn Ernest G.
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