Accelerators for forming cationic technetium complexes useful as

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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260429R, 260440, 260446, 424 9, A61K 4300, A61K 4900, C07F 966, C07F 990

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044552912

ABSTRACT:
A composition for preparing cationic lipophilic technetium complexes is described. The composition comprises an admixture of (a) an accelerator compound selected from the group of water-soluble organic bidentate ligands that are capable of coordinating with technetium to form a 4 to 6 member ring and (b) a target-seeking ligand, or aqueous salt thereof, having the structure indicated in formulas I, II or III. The accelerator compound has a weaker coordinating bond with technetium than the target-seeking ligand has with technetium.

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