Induced nuclear reactions: processes – systems – and elements – Nuclear transmutation
Patent
1996-09-13
1999-05-11
Behrend, Harvey E.
Induced nuclear reactions: processes, systems, and elements
Nuclear transmutation
376110, 376159, 376458, G21H5/00
Patent
active
059036222
ABSTRACT:
A source for boron neutron capture therapy (BNCT) comprises a body of photoneutron emitter that includes heavy water and is closely surrounded in heat-imparting relationship by target material; one or more electron linear accelerators for supplying electron radiation having energy of substantially 2 to 10 MeV and for impinging such radiation on the target material, whereby photoneutrons are produced and heat is absorbed from the target material by the body of photoneutron emitter. The heavy water is circulated through a cooling arrangement to remove heat. A tank, desirably cylindrical or spherical, contains the heavy water, and a desired number of the electron accelerators circumferentially surround the tank and the target material as preferably made up of thin plates of metallic tungsten. Neutrons generated within the tank are passed through a surrounding region containing neutron filtering and moderating materials and through neutron delimiting structure to produce a beam or beams of epithermal neutrons normally having a minimum flux intensity level of 1.0.times.10.sup.9 neutrons per square centimeter per second. Such beam or beams of epithermal neutrons are passed through gamma ray attenuating material to provide the required epithermal neutrons for BNCT use.
REFERENCES:
patent: 2868987 (1959-01-01), Salsig, Jr. et al.
patent: 2902613 (1959-09-01), Baldwin et al.
patent: 2933442 (1960-04-01), Lawrence et al.
patent: 3833814 (1974-09-01), Nablo
patent: 4251726 (1981-02-01), Alvarez
patent: 4381280 (1983-04-01), Roberts
patent: 4666651 (1987-05-01), Barjon et al.
patent: 4756866 (1988-07-01), Alvarez
patent: 5392319 (1995-02-01), Eggers
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, Plenum Press, N.Y. (1990), pp. 83-95, article by Wheeler et al.
Nuclear Technology, vol. 55, (Dec. 1981), pp. 642-655, Oka et al.
Int. J. Appl. Radiat. Isot., vol. 24 (1973), pp. 124-126, Lindner et al (I).
Advances in Neutron Capture Therapy, Plenum Press N.Y., (1993) pp. 85-88, article by Rief et al.
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, Plenum Press, N.Y. (1990), pp. 235-245, article by Becker et al.
Progress in Neutron Capture Therapy for Cancer, Plenum Press N.Y. (1992), pp. 53-56, article by Choi et al.
Strahlentherapie und Onkologie, vol. 165, (1989), pp. 87-90, Less et al.
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, Plenum Press, N.Y. (1990), pp. 97-107, Harrington.
Nuc. Inst. and Methods, vol. 119, No. 2, (Jul. 1974), pp. 217-227, Harling.
Int. J. Appl. Radiat. Isot., vol. 24 (1973), pp. 121-124, Lindner et al.
Jones, et al, Feasibility Study of the Application of a Linear Electron Accelerator to BNCT, Abstracts for the Twelfth International Conference on the Application of Accelerators in Research & Industry, Nov. 2-5, 1992, p. 59.
Nigg, et al, Conceptual Physics Design of an Epithermal-Neutron Facility for Neutron Capture Therapy at the GeorgieaTech Research Reactor, Neutron Capture Therapy-I, pp. 146-147.
Auterinen et al, pp. 81-84, "Advances in Neutron Capture Therapy", Ed. Soloway et al, Plenum Press, N.Y. 1993.
Harker Yale D.
Jones James L.
Nigg David W.
Yoon Woo Y.
Behrend Harvey E.
Kirsch Alan D.
Lockheed Martin Idaho Technologies Company
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