Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-06-06
2006-06-06
Whisenant, Ethan (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S287200, C536S023100, C536S024300
Reexamination Certificate
active
07056669
ABSTRACT:
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
REFERENCES:
patent: 3619511 (1971-11-01), Ishikawa
patent: 4072576 (1978-02-01), Arwin et al.
patent: 4656127 (1987-04-01), Mundy
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4707440 (1987-11-01), Stavrianopoulos
patent: 4713347 (1987-12-01), Mitchell et al.
patent: 4755458 (1988-07-01), Rabbani et al.
patent: 4802101 (1989-01-01), Hara
patent: 4840893 (1989-06-01), Hill et al.
patent: 4851331 (1989-07-01), Vary et al.
patent: 4876187 (1989-10-01), Duck et al.
patent: 4894325 (1990-01-01), Englehardt et al.
patent: 4943523 (1990-07-01), Stavrianopoulos
patent: 4945045 (1990-07-01), Forrest et al.
patent: 4952685 (1990-08-01), Stavrianopoulos
patent: 4964972 (1990-10-01), Sagiv et al.
patent: 4988617 (1991-01-01), Landegren et al.
patent: 4994373 (1991-02-01), Stavrianopoulos et al.
patent: 5002885 (1991-03-01), Stavrianopoulos
patent: 5011769 (1991-04-01), Duck et al.
patent: 5013831 (1991-05-01), Stavrianopoulos
patent: 5015569 (1991-05-01), Pontius
patent: 5108573 (1992-04-01), Rubinstain et al.
patent: 5130238 (1992-07-01), Malek et al.
patent: 5156810 (1992-10-01), Ribi
patent: 5164319 (1992-11-01), Hafeman et al.
patent: 5171853 (1992-12-01), Thorp et al.
patent: 5175270 (1992-12-01), Nilsen et al.
patent: 5180968 (1993-01-01), Bruckenstein et al.
patent: 5187096 (1993-02-01), Giaver et al.
patent: 5194133 (1993-03-01), Clark et al.
patent: 5200051 (1993-04-01), Cozzette et al.
patent: 5238808 (1993-08-01), Bard et al.
patent: 5242828 (1993-09-01), Bergstrom et al.
patent: 5244560 (1993-09-01), Kuhr
patent: 5278043 (1994-01-01), Bannwarth et al.
patent: 5294369 (1994-03-01), Shigekawa et al.
patent: 5308754 (1994-05-01), Kankare et al.
patent: 5312527 (1994-05-01), Mikkelsen et al.
patent: 5324457 (1994-06-01), Zhang et al.
patent: 5328824 (1994-07-01), Ward et al.
patent: 5391272 (1995-02-01), O'Daly et al.
patent: 5403451 (1995-04-01), Rivello et al.
patent: 5403711 (1995-04-01), Walder et al.
patent: 5409818 (1995-04-01), Davey et al.
patent: 5443701 (1995-08-01), Willner et al.
patent: 5455166 (1995-10-01), Walker
patent: 5474796 (1995-12-01), Brennan
patent: 5487973 (1996-01-01), Nilsen et al.
patent: 5491097 (1996-02-01), Ribi et al.
patent: 5492806 (1996-02-01), Drmanac et al.
patent: 5494810 (1996-02-01), Barany et al.
patent: 5512131 (1996-04-01), Kumar et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5532128 (1996-07-01), Eggers et al.
patent: 5534424 (1996-07-01), Uhlen et al.
patent: 5545531 (1996-08-01), Rava et al.
patent: 5547839 (1996-08-01), Dower et al.
patent: 5552270 (1996-09-01), Khrapko et al.
patent: 5565322 (1996-10-01), Heller
patent: 5571568 (1996-11-01), Ribi et al.
patent: 5591578 (1997-01-01), Meade et al.
patent: 5705348 (1998-01-01), Meade et al.
patent: 5770369 (1998-06-01), Meade et al.
patent: 5780234 (1998-07-01), Meade et al.
patent: 5824473 (1998-10-01), Meade et al.
patent: 5952172 (1999-09-01), Meade et al.
patent: 6071699 (2000-06-01), Meade et al.
patent: 6087100 (2000-07-01), Meade et al.
patent: 6090933 (2000-07-01), Kayyem et al.
patent: 6096273 (2000-08-01), Kayyem et al.
patent: 6177250 (2001-01-01), Meade et al.
patent: 6180352 (2001-01-01), Meade et al.
patent: 6200761 (2001-03-01), Meade et al.
patent: 6221583 (2001-04-01), Kayyem et al.
patent: 6232062 (2001-05-01), Kayyem et al.
patent: 6238870 (2001-05-01), Meade et al.
patent: 6258545 (2001-07-01), Meade et al.
patent: 6264825 (2001-07-01), Blackburn et al.
patent: 6265155 (2001-07-01), Meade et al.
patent: 6268149 (2001-07-01), Meade et al.
patent: 6277576 (2001-08-01), Meade et al.
patent: 6290839 (2001-09-01), Kayyem et al.
patent: 6291188 (2001-09-01), Meade et al.
patent: 6432723 (2002-08-01), Plaxco et al.
patent: 6479240 (2002-11-01), Kayyem et al.
patent: 6495323 (2002-12-01), Kayyem et al.
patent: 6528266 (2003-03-01), Meade et al.
patent: 6600026 (2003-07-01), Yu
patent: 6686150 (2004-02-01), Blackburn et al.
patent: 6740518 (2004-05-01), Duong et al.
patent: 6761816 (2004-07-01), Blackburn et al.
patent: 2001/0034033 (2001-10-01), Meade at al.
patent: 2002/0006643 (2002-01-01), Kayyen et al.
patent: 2003/0003473 (2003-01-01), Kayyem et al.
patent: 2003/0148328 (2003-08-01), Kayyem et al.
patent: 2003/0150723 (2003-08-01), Kayyem et al.
patent: 2003/0170677 (2003-09-01), Meade et al.
patent: 2004/0101890 (2004-05-01), Meade et al.
patent: 2004/0146909 (2004-07-01), Duong et al.
patent: 2005/0003399 (2005-01-01), Blackburn et al.
patent: 0 142 301 (1985-05-01), None
patent: 0 213 825 (1987-03-01), None
patent: 0 229 943 (1987-07-01), None
patent: 0 317 074 (1989-05-01), None
patent: 0 339 821 (1989-11-01), None
patent: 0 371 437 (1990-06-01), None
patent: 0 439 036 (1991-07-01), None
patent: 0 476 319 (1992-04-01), None
patent: 0 599 337 (1994-06-01), None
patent: 0 668 502 (1995-08-01), None
patent: 63-238166 (1988-10-01), None
patent: WO 90/05732 (1990-05-01), None
patent: WO 91/13075 (1991-09-01), None
patent: WO 91/13075 (1991-09-01), None
patent: WO 92/10757 (1992-06-01), None
patent: WO 92/15712 (1992-09-01), None
patent: WO 93/10267 (1993-05-01), None
patent: WO 93/25898 (1993-12-01), None
patent: WO 94/22889 (1994-10-01), None
patent: WO 95/00666 (1995-01-01), None
patent: WO 95/00667 (1995-01-01), None
patent: WO 95/05480 (1995-02-01), None
patent: WO 95/05480 (1995-02-01), None
patent: WO 95/00659 (1995-05-01), None
patent: WO 95/34816 (1995-12-01), None
patent: WO 96/06946 (1996-03-01), None
patent: WO 96/10176 (1996-04-01), None
Aizawa, M., et al., “Integrated molecular systems for biosensors,”Sens. Actuators B Chem.24(1&3):1-5 (Mar. 1995).
Alexander, V., “Design and Synthesis of Macrocyclic Ligands and Their Complexes of Lanthanides and Actinides,”Chem. Rev.95(2):273-342 (Mar.-Apr. 1995).
Alsfasser, R., et al, “Novel Building Blocks for Biomimetic Assemblies. Synthesis, Characterization and Spectroscopic and Electrochemical Properties of New Bidendate Ligands Derived from Lysine and Cystine and Their Complexes with Bis(2,2′-bipyridine)ruthenium(ii).”Inorg. Chem.35(3):626-636 (Jan. 1996).
Arkin, M., et al., “Evidence for Photoselectron Transfer Through DNA Intercalation,”J. Inorg. Biochem. Abstr., 6th Int. Conf. Bioinorg. Chem.51(1&2):526 (1993).
Arkin, M., et al., “Rates of DNA-Mediated Electron Transfer Between Metallointercalators,”Science273(5274):475-480 (Jul. 1996).
Bains, W., et al., “A novel method for nucleic acid sequence determination,”J. Theor. Biol.135(3):303-307 (Dec. 1988).
Bain, C., et al., “Formation of monolayers by the coadsorption of thiols on gold: variation in the length of the alkyl chain,”J. Am. Chem. Soc.111(18):7164-7175 (Aug. 1989).
Barany, F., “Genetic disease detection and DNA amplification using cloned thermostable ligase,”Proc. Natl. Acad. Sci. USA88(1):189-193 (Jan. 1991).
Beattie, K., et al., “Advances in Genosensor Research”,Clin. Chem.41(5):700-706 (1995).
Beattie, K., et al., “Genosensor Technology,”Clin. Chem.39(4):719-722 (1993).
Bignozzi, C., et al., “A simple poly(pyridine)ruthenium(II) photosensitizer: (2,2′-bipyridine)tetracyanoruthenate(II),”J. Am. Chem. Soc.108(24):7872-7873 (Nov. 1986).
Bilewicz, R., et al., “Monomolecular Langmuir-Blodgett films at electrodes: electrochemistry at single molecule ‘gate site’,”Langmuir11(6):2256-2266 (Jun. 1995).
Bjerrum, M., et al., “Electron transfer in ruthenium-modified proteins,”J. Bioenerg. Biomembr.27(3):295-302 (Jun. 1995).
Blonder, R., et al., “Application of Redox Enzymes for Probing the Antigen-Antibody Association at the Monolayer Interfaces: Development of Amperomet
Kayyem Jon Faiz
O'Connor Stephen D.
Clinical Micro Sensors, Inc.
Dorsey & Whitney LLP
Silva Robin M.
Whisenant Ethan
LandOfFree
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