Abuse resistant drugs, method of use and method of making

Details Abuse resistant drugs, method of use and method of making Abuse resistant drugs, method of use and method of making

2011-06-07

2011-06-07

Foley, Shanon A (Department: 1648)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S400000, C424S464000, C424S451000, C424S489000, C514S282000, C514S259300, C514S317000, C514S652000, C514S646000

Reexamination Certificate

active

07955619

ABSTRACT:
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.

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