Absorption information measuring method and apparatus of scatter

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

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600322, 600473, 600476, 356432, A61B 500

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059831219

ABSTRACT:
A method characterized by making modulated light having a predetermined modulation frequency component, incident to a scattering medium, receiving the modulated light having propagated inside the scattering medium to acquire measurement signals, detecting signals of the foregoing modulation frequency component from the measurement signals, obtaining amplitudes and inclinations of phase against modulation angular frequency, of the signals of the foregoing modulation frequency component, calculating a difference between absorption coefficients being primary information, based on a predetermined relation among the amplitudes, the inclinations of phase against modulation angular frequency and the difference between absorption coefficients, and calculating a difference of concentration of an absorptive constituent being secondary information, based on the difference between absorption coefficients.

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Tsuchiya et al, "Non-Invasive Spectroscopy of Variously Shaped Turbid Media Like Human Tissue Based on the Microscopic Beer-Lambert Law", OSA Tops on Biomedical Optical Spectroscopy and Diagnostics 1996, vol. 3, 1996 Optical Society of America, pp. 98-100.
Tsuchiya et al, "Non-Invasive Spectroscopy of Turbid Media Having Various Non-Reentrant Surfaces (1)", Japan Optics '95, pp. 61-62.
Tsuchiya et al, "Frequency Domain Analysis of Photon Migration Based on the Microscopic Beer-Lambert Law", Jpn. J. Appl. Phys., vol. 35, 1996, pp. 4848-4851.

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