Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1985-05-20
1987-04-07
Rosen, Sam
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424127, 514 2, 514114, 514257, 514264, 514425, 514588, 514614, 514632, 514634, 514645, A61K 3750
Patent
active
046560343
ABSTRACT:
The absorption of a scavenger of oxygen free radicals generated at the time of reperfusion or the absorption of an agent preventing the cytotoxic effects on healthy cells in a mammal. e.g. superoxide dismutase or S-aminotrimethyleneaminoethyl thiophosphate is enhanced by substantially simultaneously administering an absorption enhancing agent therefore, e.g. hydroxylamine or a non-toxic salt thereof. It is also part of the invention to inject WR-2721 intravenously or intramuscularly as a scavenger of oxygen free radicals even in the absence of an absorption enhancing agent.
REFERENCES:
patent: 3629410 (1971-12-01), Heiffer et al.
patent: 4292311 (1981-09-01), Sarnoff
Mil'chakov et al.-Chem. Abst. vol. 98 (1983) p. 46932g.
Lankin et al.-Chem. Abst. vol. 97 (1982) p. 21610s.
Rosen Sam
Survival Technology Inc.
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