Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...
Reexamination Certificate
2005-10-04
2005-10-04
Naff, David M. (Department: 1651)
Chemistry: molecular biology and microbiology
Maintaining blood or sperm in a physiologically active state...
C424S529000, C435S238000, C435S283100, C530S412000, C530S413000, C530S415000
Reexamination Certificate
active
06951713
ABSTRACT:
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition, while substantially maintaining a desired biological activity of the biological composition. The device comprises highly porous adsorbent particles, and the adsorbent particles are immobilized by an inert matrix. The matrix containing the particles is contained in a housing, and the particles range in diameter from about 1 μm to about 200 μm. The matrix can be fibrous, and the particles can have a surface area greater than 750 m2/g and a pore diameter between about 25 and 800 Å. The device can be used to adsorb and remove a pathogen-inactivating compound that is a nucleic acid-binding compound such as psoralen, an acridine derivative or a dye from a biological composition such as a blood product.
REFERENCES:
patent: 3238056 (1966-03-01), Pall et al.
patent: 3729457 (1973-04-01), Davankov et al.
patent: 3975481 (1976-08-01), Baumgaertner
patent: 4064042 (1977-12-01), Kunin
patent: 4110391 (1978-08-01), Berzen et al.
patent: 4160059 (1979-07-01), Samejima
patent: 4202775 (1980-05-01), Abe et al.
patent: 4309247 (1982-01-01), Hou et al.
patent: 4390619 (1983-06-01), Harmening-Pittiglio
patent: 4460530 (1984-07-01), Hanson et al.
patent: 4576715 (1986-03-01), Michaels et al.
patent: 4594202 (1986-06-01), Pall et al.
patent: 4664683 (1987-05-01), Degen et al.
patent: 4684521 (1987-08-01), Edelson
patent: 4693981 (1987-09-01), Wiesehahn et al.
patent: 4727027 (1988-02-01), Wiesehahn et al.
patent: 4728432 (1988-03-01), Sugiyama et al.
patent: 4748120 (1988-05-01), Wiesehahn
patent: 4777069 (1988-10-01), Cederberg et al.
patent: 4880843 (1989-11-01), Stein
patent: 4925880 (1990-05-01), Stein
patent: 4935141 (1990-06-01), Buck et al.
patent: 4943373 (1990-07-01), Onishi et al.
patent: 4959148 (1990-09-01), Clark, III
patent: 4985153 (1991-01-01), Kuroda et al.
patent: 5019311 (1991-05-01), Koslow
patent: 5030352 (1991-07-01), Varady et al.
patent: 5037857 (1991-08-01), Maroldo et al.
patent: 5094960 (1992-03-01), Bonomo
patent: 5100564 (1992-03-01), Pall et al.
patent: 5128048 (1992-07-01), Stewart et al.
patent: 5137926 (1992-08-01), Maroldo et al.
patent: 5147722 (1992-09-01), Koslow
patent: 5190657 (1993-03-01), Heagle et al.
patent: 5234608 (1993-08-01), Duff
patent: 5269917 (1993-12-01), Stankowski
patent: 5279742 (1994-01-01), Markell et al.
patent: 5288605 (1994-02-01), Lin et al.
patent: 5328758 (1994-07-01), Markell et al.
patent: 5354262 (1994-10-01), Boehringer et al.
patent: 5407581 (1995-04-01), Onodera et al.
patent: 5418130 (1995-05-01), Platz et al.
patent: 5455040 (1995-10-01), Marchant
patent: 5456845 (1995-10-01), Nishimura et al.
patent: 5459030 (1995-10-01), Lin et al.
patent: 5468536 (1995-11-01), Whitcomb et al.
patent: 5482828 (1996-01-01), Lin et al.
patent: 5486293 (1996-01-01), Boschetti et al.
patent: 5486410 (1996-01-01), Groeger et al.
patent: 5501795 (1996-03-01), Pall et al.
patent: 5504163 (1996-04-01), Tegen et al.
patent: 5531902 (1996-07-01), Gallup
patent: 5543062 (1996-08-01), Nishimura
patent: 5556541 (1996-09-01), Ruschke
patent: 5559250 (1996-09-01), Cook et al.
patent: 5571666 (1996-11-01), Floyd et al.
patent: 5593823 (1997-01-01), Wollowitz et al.
patent: 5605746 (1997-02-01), Groeger et al.
patent: 5607766 (1997-03-01), Berger
patent: 5616254 (1997-04-01), Pall et al.
patent: 5639376 (1997-06-01), Lee et al.
patent: 5660731 (1997-08-01), Piechocki et al.
patent: 5662728 (1997-09-01), Groeger
patent: 5773384 (1998-06-01), Davankov et al.
patent: 5817354 (1998-10-01), Mozaffar et al.
patent: 5871900 (1999-02-01), Wollowitz et al.
patent: 5882517 (1999-03-01), Chen et al.
patent: 5883256 (1999-03-01), Schuler et al.
patent: 6228995 (2001-05-01), Lee
patent: 6294361 (2001-09-01), Horowitz et al.
patent: 6319662 (2001-11-01), Foley et al.
patent: 6348309 (2002-02-01), Mohr et al.
patent: 6544727 (2003-04-01), Hei
patent: 2002/0045228 (2002-04-01), Hei
patent: 2002/0094568 (2002-07-01), Hei
patent: 2002/0115585 (2002-08-01), Hei
patent: 2002/0192632 (2002-12-01), Hei et al.
patent: 2004/0185544 (2004-09-01), Hei
patent: 2004/0185553 (2004-09-01), Hei
patent: 6339190 (1991-04-01), None
patent: 2065842 (1999-12-01), None
patent: 27 21 511 (1977-11-01), None
patent: 249 274 (1987-09-01), None
patent: 3819000 (1989-12-01), None
patent: 099 586 (1983-07-01), None
patent: 230 247 (1987-07-01), None
patent: 0 366 946 (1990-05-01), None
patent: 0 776 668 (1996-10-01), None
patent: 62-283198 (1987-12-01), None
patent: 03-229610 (1991-10-01), None
patent: WO 83/00023 (1983-01-01), None
patent: WO 91/03933 (1991-04-01), None
patent: WO 94/11556 (1994-05-01), None
patent: WO 94/27433 (1994-12-01), None
patent: WO 95/00631 (1995-01-01), None
patent: WO 95/18665 (1995-07-01), None
patent: WO 96/39818 (1996-12-01), None
patent: WO 96/40857 (1996-12-01), None
patent: WO 97/18844 (1997-05-01), None
patent: WO 97/37536 (1997-10-01), None
patent: WO 98/30327 (1998-07-01), None
patent: WO 99/34914 (1999-07-01), None
patent: WO 99/34915 (1999-07-01), None
patent: WO 99/37340 (1999-07-01), None
English Translation of PCT Application PCT/DE90/00691.
510(k) Notification submitted to the U.S. Food & Drug Administration, Asahi Medical Co., Ltd., Tokyo, Japan (Dec. 5, 1988).
Andrade, J.D., et al., “Coated adsorbents for direct blood perfusion: Hema/activated carbon”, vol. XVII Trans. Amer. Soc. Artf. Int. Organs pp. 222-228 (1971).
Artuc et al. “Reversible binding of 5- and 8-methoxypsoralen to human serum proteins (albumin) and to epidermis in vitro” Brit. J. Derm. 101:669-677 (1979).
Bertolini, F. et al., “Platelet concentrates stored in synthetic medium after filtration,” Vox Sang 67:82-86 (1992).
Bock, M., et al., “White cell depletion of single-donor platelet preparations by a new adsorption filter,” Transfusion 31:333-334 (1991).
Bogusz M. et al. “Isolation of drugs from blood and tissues with XAD-2 bags” Forensic Sci. Int'l. 12:73-82 (1978).
Boomgaard, M.N. et al., “In vitro evaluation of platelet concentrates, prepared from pooled buffy coats, stored for 8 days after filtration”, Transfusion 34:311-316 (1994).
Brettel T.A., and Saferstein, R., “Forensic science” Anal. Chem., 59:162-174 (1987).
Carmen R. “The selection of plastic materials for blood bags” Trnas. Med. Rev. 7:1 1-10 (1993).
Chandy, T., and Sharma, C.P., “Polylysine-immoblilized chitosan beads as adsorbents for bilitubin,” Artificial Organs 16:568-576 (1992).
Chaplin, H. et al. “Frozen storage of 11 units of sickle cell red cells for autologous transfusion of a single patient” Transfusion vol. 26:4 pp. 341-345 (1986).
Coli L. et al. “Phosphate removal by resin hemoperfusion efficacy and biocompatibility of a new exchange” Biomat. Art Cells & Immob. Biotech., 20:1153-1163 (1992).
Courtney, J.M., et al., “Monitoring of the blood response in blood purification,” Artificial Organs 17:260-266 (1993).
Cruse, J.M. and Lewis, R.E.Illustrated Dictionary of Immunology, CRC Press (1995) p. 37.
Davankov, V.A., and Tsyurupa, M.P., “Structure and properties of hypercrosslinked polystyrene-the first representative of a new class of polymer networks,”Reactive Polymers13 Elsevier Science Pub. B.V., Amsterdam pp. 27-42 (1990).
Denti, E. et al. (Jul.-Aug. 1977) “Evaluation of novel sorbent systems for joint hemodialysis and hemoperfusion” Med. Instrument. 11(4):212-214.
Dodd et al. (1991) “Inactivation of Viruses in Platelet Suspensions that Retain Their In Vitro Characteristics: Comparison of Psoralen-ultraviolet A and Merocyanine 540 Visible Light Methods,” Transfusion 31:483-490.
Dunlop, E.H. and Williams, R., “Physico-chemical aspects of the removal of protein-bound substances by charcoal and other adsorbents of potential value in systems of artificial liver support: Part 2- Kinetics of removal,” Med. & Biol. Eng. & Comput., 16:350-3
Clarke Michael S.
Hei Derek J.
Cerus Corporation
Morrison & Foerster / LLP
Naff David M.
LandOfFree
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