Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Chemical aftertreatment – e.g. – acylation – methylation – etc.
Patent
1996-01-24
1999-07-06
Richter, Johann
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Chemical aftertreatment, e.g., acylation, methylation, etc.
530412, 530351, A61K 3800
Patent
active
059198982
ABSTRACT:
An adsorbent for removing at least one interleukin selected from the group consisting of inerleukin-1, interleukin-2, interleukin-6 and interluekin-8 and/or TNF, which comprises a porous water-insolube carrier and a compound satisfying the value of log P of at least 2.50, in which P is a distribution coefficient in an octanol-water system and being immobilized onto the carrier, a process for removing the above IL(s) and/or TNF by the adsorbent and an adsorber comprising the adsorbent. According to the present invention, IL(s) and TNF in body fluid can be efficiently absorbed using the above-mentioned adsorbent.
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Furuyoshi Shigeo
Nakatani Masaru
Takata Satoshi
Delaney Patrick R.
Kanegafuchi Kagaku Kogyo & Kabushiki Kaisha
Richter Johann
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