Absorbable pharmaceutical compositions based on poly(alkylene ox

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 19, 424 32, 528272, A61K 3174, A61K 932, A61K 922, A61K 952

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active

041861892

ABSTRACT:
Absorbable polymers derived from alkylene oxalates are formulated with drugs and introduced into the body to provide a slow, sustained release of the drug over an extended period of time in accordance with the rate of absorption of the polymer. Polymers of alkylene oxalates, particularly wherein the alkylene moiety is C.sub.3 to C.sub.16, are biodegradable in animal tissue and absorb with minimal adverse tissue reaction.

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Alksnis et al., J. Polym. Sci., Polym. Chem. Ed., 15, 1855, (1977).
Savinov et al., Polym. Sci., U.S.S.R., 6, 1475, (1964).

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