Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1996-05-28
1999-02-09
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
A61F 202
Patent
active
058690808
ABSTRACT:
Absorbable implant materials having controlled porosity are formed by a method comprising the steps of: providing a dispersion of a bioabsorbable polymer, such as collagen, in a first solvent, such as water; adding particles of a second material, e.g. frozen water droplets or ice particles to the dispersion; followed by freezing the dispersion to form a frozen dispersion having the particles embedded therein, and removing both the first solvent and the second material from the frozen dispersion by freeze-drying or solvent extraction to leave the porous implant material. The invention also encompasses the use of such implant materials for wound healing applications.
REFERENCES:
patent: 4606910 (1986-08-01), Sawyer
patent: 5326350 (1994-07-01), Li
patent: 5466462 (1995-11-01), Rosenthal et al.
patent: 5565210 (1996-10-01), Rosenthal et al.
patent: 5571181 (1996-11-01), Li
patent: 5610148 (1997-03-01), Brown
Harvey Wilson
Light Nicholas D.
McGregor James
Watt Paul W.
Azpuru Carlos A.
Farmer Andrew C.
Johnson & Johnson Medical Inc.
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